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                                May 11, 2023

       Danny Yeung
       Chief Executive Officer
       Prenetics Global Limited
       Unit 701-706, K11 Atelier King   s Road 728 King   s Road, Quarry Bay
       Hong Kong

                                                        Re: Prenetics Global
Limited
                                                            Post-Effective
Amendment for Registration Statement on Form F-1
                                                            Filed May 1, 2023
                                                            File No. 333-265284

       Dear Danny Yeung:

              We have reviewed your post-effective amendment and have the
following comments. In
       some of our comments, we may ask you to provide us with information so
we may better
       understand your disclosure.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comments apply to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to these comments, we may have additional comments.

       Post-Effective Amendment for Registration Statement on Form F-1 filed on
May 1, 2023

       Cover Page

   1.                                                   We note that on the
cover you state that Prenetics Global Limited is a Cayman Islands
                                                        holding company with
operations primarily conducted by its subsidiaries, which we
                                                        understand operate in
Hong Kong and other jurisdictions. Please revise provide a cross-
                                                        reference to your
detailed discussion of risks facing the company and the offering as a
                                                        result of your
organizational structure.
   2.                                                   Provide prominent
disclosure about the legal and operational risks associated with being
                                                        based in or having the
majority of the company   s operations in China. Your disclosure
                                                        should make clear
whether these risks could result in a material change in your operations
                                                        and/or the value of
your securities or could significantly limit or completely hinder your
                                                        ability to offer
securities to investors and cause the value of your securities to significantly
 Danny Yeung
FirstName  LastNameDanny
Prenetics Global Limited Yeung
Comapany
May        NamePrenetics Global Limited
     11, 2023
May 11,
Page 2 2023 Page 2
FirstName LastName
         decline or be worthless. Your disclosure should address how recent
statements and
         regulatory actions by China   s government, such as those related to
the use of variable
         interest entities and data security or anti-monopoly concerns, have or
may impact the
         company   s ability to conduct its business, accept foreign
investments, or list on a U.S. or
         other foreign exchange. Also disclose that regulatory actions related
to data security or
         anti-monopoly concerns in Hong Kong or Macau have or may impact your
ability to
         conduct your business, accept foreign investments, or list on a U.S.
or foreign exchange.
         Please disclose the location of your auditor   s headquarters and
whether and how the
         Holding Foreign Companies Accountable Act, as amended by the
Consolidated
         Appropriations Act, 2023, and related regulations will affect your
company. Your
         prospectus summary should address, but not necessarily be limited to,
the risks
         highlighted on the prospectus cover page.
3.       Disclose specifically which entity(ies) conduct the company's
operations. Disclose, if true,
         that your subsidiaries conduct operations in China.

4.       Provide a description of how cash is transferred through your
organization and disclose
         your intentions to distribute earnings. State whether any transfers,
dividends, or
         distributions have been made to date between the holding company, its
subsidiaries, or to
         investors, and quantify the amounts where applicable. Provide a
cross-reference to the
         consolidated financial statements.
Prospectus Summary, page 1

5.       Disclose each permission or approval that you or your subsidiaries are
required to obtain
         from Chinese authorities to operate your business and to offer the
securities being
         registered to foreign investors. State whether you or your
subsidiaries are covered by
         permissions requirements from the China Securities Regulatory
Commission (CSRC),
         Cyberspace Administration of China (CAC) or any other governmental
agency that is
         required to approve your operations, and state affirmatively whether
you have received all
         requisite permissions or approvals and whether any permissions or
approvals have been
         denied. Please also describe the consequences to you and your
investors if you or your
         subsidiaries: (i) do not receive or maintain such permissions or
approvals, (ii)
         inadvertently conclude that such permissions or approvals are not
required, or (iii)
         applicable laws, regulations, or interpretations change and you are
required to obtain such
         permissions or approvals in the future.
6.       Provide a clear description of how cash is transferred through your
organization. Disclose
         your intentions to distribute earnings. Quantify any cash flows and
transfers of other
         assets by type that have occurred between the holding company and its
subsidiaries, and
         direction of transfer. Quantify any dividends or distributions that a
subsidiary have made
         to the holding company and which entity made such transfer, and their
tax consequences.
         Similarly quantify dividends or distributions made to U.S. investors,
the source, and their
         tax consequences. Your disclosure should make clear if no transfers,
dividends, or
 Danny Yeung
FirstName  LastNameDanny
Prenetics Global Limited Yeung
Comapany
May        NamePrenetics Global Limited
     11, 2023
May 11,
Page 3 2023 Page 3
FirstName LastName
         distributions have been made to date. Describe any restrictions on
foreign exchange and
         your ability to transfer cash between entities, across borders, and to
U.S. investors.
         Describe any restrictions and limitations on your ability to
distribute earnings from the
         company, including your subsidiaries, to the parent company and U.S.
investors.
7.       Disclose that trading in your securities may be prohibited under the
Holding Foreign
         Companies Accountable Act, as amended by the Consolidated
Appropriations Act, 2023,
         and related regulations if the PCAOB determines that it cannot inspect
or investigate
         completely your auditor for a period of two consecutive years, and
that as a result an
         exchange may determine to delist your securities.
Prospectus Summary
Summary Risk Factors, page 3

8.       In your Summary Risk Factors, disclose the risks that your corporate
structure and being
         based in or having the majority of the company   s operations in China
poses to investors.
         In particular, describe the significant regulatory, liquidity, and
enforcement risks with
         cross-references to the more detailed discussion of these risks in the
prospectus. For
         example, specifically discuss risks arising from the legal system in
China, including risks
         and uncertainties regarding the enforcement of laws and that rules and
regulations in
         China can change quickly with little advance notice; and the risk that
the Chinese
         government may intervene or influence your operations at any time, or
may exert more
         control over offerings conducted overseas and/or foreign investment in
China-based
         issuers, which could result in a material change in your operations
and/or the value of the
         securities you are registering for sale. Acknowledge any risks that
any actions by the
         Chinese government to exert more oversight and control over offerings
that are conducted
         overseas and/or foreign investment in China-based issuers could
significantly limit or
         completely hinder your ability to offer or continue to offer
securities to investors and
         cause the value of such securities to significantly decline or be
worthless.
Risk Factors, page 7

9.       Please expand your risk factors to disclose that the Holding Foreign
Companies
         Accountable Act, as amended by the Consolidated Appropriations Act,
2023, decreases
         the number of consecutive    non-inspection years    from three years
to two years, and thus,
         reduces the time before your securities may be prohibited from trading
or delisted. Update
         your disclosure to describe the potential consequences to you if the
PRC adopts positions
         at any time in the future that would prevent the PCAOB from continuing
to inspect or
         investigate completely accounting firms headquartered in mainland
China or Hong Kong.
10.      In light of recent events indicating greater oversight by the
Cyberspace Administration of
         China (CAC) over data security, particularly for companies seeking to
list on a foreign
         exchange, please revise your disclosure to explain how this oversight
impacts your
         business and your offering and to what extent you believe that you are
compliant with the
         regulations or policies that have been issued by the CAC to date.
Also, provide risk factor
 Danny Yeung
Prenetics Global Limited
May 11, 2023
Page 4
         disclosure to explain whether there are any commensurate laws or
regulations in Hong
         Kong or Macau which result in oversight over data security and explain
how this
         oversight impacts the company   s business and the offering and to
what extent the
         company believes that it is compliant with the regulations or policies
that have been
         issued.
The mainland Chinese government has significant oversight, discretion and
control over..., page
22

11.      We note your disclosure about having business operations in Hong Kong
and not in
         Mainland China and the risks that come with having direct Chinese
government oversight
         authority. Disclose in this Risk Factor, as you do on page 51, that
you believe there is
         significant market opportunity for you in Mainland China for early
detection of
         cancer. Also, given recent statements by the Chinese government
indicating an intent to
         exert more oversight and control over offerings that are conducted
overseas and/or foreign
         investment in China-based issuers, acknowledge the risk that any such
action could
         significantly limit or completely hinder your ability to offer or
continue to offer securities
         to investors and cause the value of such securities to significantly
decline or be worthless.

General

12.    We note your separate section that discloses "Enforceability of civil
liabilities and agent
       for service of process in the United States" on page 147. Please revise
to provide the
       information required by Item 101(g)(1)(i)(ii) and (iv) of Regulation
S-K.
       Include Summary Risk Factor and Risk Factor disclosure discussing where
your executive
       officers and directors are located, specifically addressing the
difficulty of bringing actions
       against individuals located in China (or other foreign jurisdictions)
and enforcing
       judgments against them.
FirstName LastNameDanny Yeung
13.    We note your definition of "mainland China" excludes Hong Kong and
Macau. Please
Comapany    NamePrenetics
       revise this definitionGlobal  Limited
                              to clarify that the legal and operational risks
associated with
May 11,operating
         2023 Pagein China
                     4      also apply to operations in Hong Kong and Macau.
FirstName LastName
 Danny Yeung
FirstName  LastNameDanny
Prenetics Global Limited Yeung
Comapany
May        NamePrenetics Global Limited
     11, 2023
May 11,
Page 5 2023 Page 5
FirstName LastName
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

      Please contact Nicholas O'Leary at 202-551-4451 or Margaret Schwartz at
202-551-
7153 with any other questions.



                                                          Sincerely,

                                                          Division of
Corporation Finance
                                                          Office of Industrial
Applications and
                                                          Services
cc:      Jonathan Stone, Esq.